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Objective To explore the impact of blood-activatingand qi-nourishing therapy on the hypercoagulable state of rats after femur fracture.Methods One hundred and twenty SD rats were randomly divided into 4 groups,namely normal group,model group,low-molecular-weight heparin(LMWH) group,combination group (LMWH + Tongmai Decoction),30 rats in each group.The rat model of femur fracture was established.After successful modeling,LMWH group was given subcutaneous injection of LMWH 600 U/kg,and the combination group was given subcutaneous injection of LMWH 600 U/kg together with gastric gavage of Tongmai Decoction,the model group was given subcutaneous injection of the same volume of normal saline.The treatment lasted for 1-7 days after the surgery.The pathologic features of the left great saphenous vein were observed by HE staining method,and the relative volume,thickness and quantity of the blood vessels were also measured.The plasma D-dimer (D-D) and fibrinogen (FIB) levels were determined by biochemical analyzer,and the plasma levels of whole blood viscosity at low shear rate (WBV-lsr) and whole blood viscosity at high shear rate (WBV-hsr) were measured with hemodynamic detector.Results On day 7 after the modeling,less endothelium cells,agglomerative red cells,and large thrombi were found in the great saphenous vein tissue section of the model group under microscope.Compared with the normal group,the levels of D-D,FIB,WBV-lsr and WBV-hsr in the model group at various time points were increased,the difference being significant (P ＜ 0.05).After 7-day treatment,the levels of D-D,FIB,WBV-lsr and WBV-hsr in LMWH group and combination group were lower than those of the odel group,and the decrease in the combination group was superior to LMWH group(P ＜ 0.05).The blood vessel endothelium cells in the combination group were arranged neatly with same cellular width while without enlargement or swelling,the effect being superior to that of LMWH group.Conclusion Blood-activating and Qi-nourishing therapy can effectively relieve hypercoagulable state of rats after femur fracture.
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Objective To discuss the effect of dry powder from stone of Garcinia oblongifolia in south of the Five Ridges on refractory Ⅲ and Ⅳ stage bedsore.Methods 120 cases of patients with refractory Ⅲ and Ⅳ stage pressure sore were randomly divided into the treatment group and the control group with 60 cases in each group.The treatment group applied dry powder from stone of Garcinia oblongifolia in south of the Five Ridges,while the control group used conventional infrared irradiation plus chloramphenicol powder treatment method.The treatment effect was compared between two groups.Results There were significnat differences in clinical efficacy,pain relief and cure time between the treatment group and the control group,and the treatment group acquired better effect than the control group.Conclusions The clinical efficacy,pain relief and healing time of the treatment group in the treatment of refractory Ⅲ and Ⅳ stage pressure ulcer was superior to the control group,and without skin lesions and human adverse reaction,and with the advantages of simple operation,quick,good curative effect,no pain to the patient,easy to accept and no toxic side effect.
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Objective To study the effects of wet paking the ligustrazine phosphate to cure the effusion when using chemotherapy medicine. Methods Divided 120 patients into 2 groups randomly. In the experimental group, ligustrazine phosphate was used to cure the effusion, while in the control group, the traditional method was used. Compared the effects of differences between the two groups. Results The effects about curing the effusion in the experimental group was significant better than those of in the control group. Conclusion It is an effective method about wet packing the ligustrazine phosphate to cure the effusion when using chemotherapy medicine.
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Objective To study the effect of using humane nursing among out-patients in transfusion room. Methods 4 500 adult patients with transfusion were selected as experiment group, and selected other 4 000 ones as control group. Humane nursing was performed in the experiment group, while traditional nursing was performed in the control group. The patients' satisfactory rates in these two groups were collected by questionnaires and compared with each other. Results The satisfactory rate in experiment group and control group were 99.4% and 83.3% respectively; the health education cover rate in these two groups were 100.0% and 93.7% respectively; the understanding rate were 81.8% and 72.3% respectively. All the rates what have mentioned above have significant differences between two groups (P
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[ Objective ] To observe the therapeutic effect of Bushen Fuhuo Decoction ( BFD) , a prescription mainly composed of Herba Epimedii, Rhizoma Drynariae, Radix Dipsaci, Radix Notoginseng, Fructus Lycii, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, etc. for non-traumatic ischemic necrosis of the femoral head (INFH) in the middle-aged and old patients. [Methods] Sixty-eight middle-aged and old paients with non-traumatic INFH were treated with BFD for 6 months. One year after treatment, the therapeutic effect was evaluated; blood lipid levels and blood rheological indexes were detected before and after treatment. [Results] Among the cases, 38 were cured, 19 markedly effective, 8 effective, 3 ineffective and the total effective rate was 95.6% . The effect of BFD on the cases at stage Ⅰ and stage Ⅱ was better than that at stage Ⅲ (P